CAS:138401-24-8   4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile
CAS:138401-24-8   4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile
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  • CAS:138401-24-8   4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile
  • CAS:138401-24-8   4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile

CAS:138401-24-8 4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile

NAME:4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile CAS:138401-24-8 MF:C25H27N3O MW:385.5 PURITY:98%

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Material Chemistry

Product introduction

NAME 4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile
CAS 138401-24-8
MF C25H27N3O
MW 385.5
DENSITY 1.15
MP 95-97°C
EINECS 604-075-6
BP 576.5±60.0 °C
STORAGE Sealed in dry,Room Temperature

Scientific Research Applications
Dual Receptor Antagonist Development
The compound has been studied for its potential as a dual receptor antagonist. In particular, research by Murugesan et al. (2002) focused on the development of dual angiotensin II and endothelin A receptor antagonists, leveraging the biphenyl core structure similar to that found in the 4'-((2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl)-[1,1'-biphenyl]-2-carbonitrile. This approach represented a novel strategy for treating hypertension 

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